Medical Director - Skin/IO

Location: Remote with ~50% domestic and international travel Shape the future of cancer care as a Medical Director, Skin/IO at Natera. In this strategic leadership role, you will provide medical expertise and scientific leadership across Natera’s oncology portfolio, with a focus on melanoma, cutaneous malignancies, and immunotherapy applications across solid tumors.

You will collaborate with cross-functional teams in research, development, medical affairs, and commercial functions to ensure the scientific integrity and clinical adoption of Natera’s oncology testing solutions. Primary Responsibilities: Clinical Adoption: Lead the clinical strategy and evidence generation for melanoma, non-melanoma skin cancers, and pan-tumor immunotherapy indications.

Partner closely with clinical development, medical affairs, and commercial teams to translate emerging evidence into meaningful clinical practice applications. Collaborate with key opinion leaders (KOLs), cooperative groups, and academic investigators to validate and expand clinical use cases for ctDNA-based diagnostics in immuno-oncology.

Provide field-facing education and strategic guidance to healthcare providers, payers, and advocacy organizations on clinical utility, interpretation, and impact of MRD and response monitoring in immune-treated populations. Identify and address barriers to adoption by aligning evidence generation, messaging, and stakeholder engagement with evolving standards of care and health system needs.

Medical Education and Communication: Serve as the medical and scientific spokesperson for skin and immuno-oncology programs, communicating clinical utility, study data, and product value to external experts and stakeholders. Partner with commercial teams to develop educational resources, medical content, and scientific training for healthcare providers and internal teams.

Provide scientific leadership during advisory boards, symposia, and investigator meetings. Representation and Advocacy: Represent Natera at national and international oncology and immunotherapy conferences, fostering relationships with key opinion leaders in melanoma and IO.

Promote a culture of scientific rigor and innovation within the medical affairs and R&D organizations. Research and Development: Collaborate on clinical trial design, data analysis, and publication strategy related to ctDNA applications in melanoma and other immune-responsive solid tumors.

Identify and cultivate academic and cooperative group partnerships to advance clinical validation and translational research in skin and pan-tumor immuno-oncology. Key Skill Sets / Responsibilities: Skin and Immuno-Oncology Expertise: Deep clinical knowledge of melanoma and cutaneous oncology, including evolving standards of care, targeted therapy, and checkpoint inhibitor use.

Expertise in immunotherapy mechanisms, response kinetics, and biomarker development across multiple solid tumor types. Provide expert medical guidance on immunotherapy-specific diagnostic development and clinical implementation.

Comprehensive Oncology Knowledge: Ability to engage across tumor types to support Natera’s broad oncology portfolio. Maintain awareness of emerging trends in liquid biopsy, precision medicine, and immune response monitoring.

Cross-Disciplinary Collaboration: Work collaboratively with research, development, commercial, and medical affairs to align medical strategy with business objectives. Partner with regulatory and clinical operations teams to ensure compliance, data quality, and clinical relevance.

Qualifications: MD. or D.

O. degree with board certification in Medical Oncology (required).

At least 5 years of experience in oncology, with clinical or research experience in melanoma, skin cancers, or immunotherapy (preferred). Strong publication or clinical trial background in immuno-oncology or translational oncology research (preferred).

Associate or full Medical Director designation commensurate with experience. Knowledge, Skills, and Abilities: Ability to rapidly learn Natera’s molecular testing technologies and apply clinical judgment to evaluate and communicate their relevance.

Strong written and verbal communication skills, including scientific presentation and education. Demonstrated success working cross-functionally with commercial, R&D, and clinical teams.

Understanding of immuno-oncology trial design, translational endpoints, and regulatory considerations. Effective project management and ability to balance multiple high-impact initiatives.

Collaborative mindset and ability to build consensus across functions. The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location.

This may differ in other locations due to cost of labor considerations. Remote USA $221,600 — $277,000 USD OUR OPPORTUNITY Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health.

Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other.

When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits.

Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www. natera.

com . Natera is proud to be an Equal Opportunity Employer.

We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents. Link: https://www.

natera. com/notice-of-data-collection-california-residents/ Please be advised that Natera will reach out to candidates with a @ natera.

com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent.

Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information: - BBB announcement on job scams - FBI Cyber Crime resource page